FF Tissues for RNA, DNA, and Protein Work
Cureline Clinical Network provides access to fully prescreened and consented patient’ samples in the FF (Fresh-Frozen) tissue format. These specimens have been prepared in strict compliance with Cureline SOP requirements and according to the CAP Research Biobank Quality Management system.
Collection Protocol Specifications:
a small piece of tissue prepared by a certified medical pathologist is snap-frozen in liquid nitrogen usually within 20 - 30 min after the surgical excision or 4 - 12 hours postmortem in autopsy cases. A standard sample weighs 0.4 - 0.7g on average and is supplied in a standard cryovial or cassette. An embedding media can be added upon request.
Therapeutic Areas:
- Oncology tissue samples: tumor and ANT FFPE (could be accompanied by cancer serum/plasma or blood)
- Inflammation and AID: synovial tissue FFPE, skin FFPE, others
- Neurological Diseases / CNS: postmortem brain tissue from patients with PD and AD).
- Normal Tissues:FFPE samples from 70+ locations.
Normal Human Tissues
- Adrenal (Category II)
- Bladder
- Blood cells (PBMC)
- Bone marrow (BM)
- Breast
- Cerebellum (Category II)
- Cerebral cortex (Category II)
- Colon (duodenum, colon, rectum)
- Endothelium
- Fallopian tube
- Fat (omental, other)
- GI tract (stomach, esophagus)
- Heart (various parts)
- Kidney (medulla and cortex)
- Liver
- Lung (including bronchioles)
- Lymph node (central)
- Muscle (striated, others)
- Ovary
- Pancreas (Category II)
- Parathyroid (Category III)
- Pituitary (Category II)
- Placenta
- Prostate
- Skin
- Spinal cord (cross-section)
- Spleen
- Testis
- Thyroid (Category II)
- Ureter
- Uterus (cervix, endometrium)