Oncology Matching HBS for Biomarker R&D

PRIMARY AND MATCHED RECURRENT / METASTATIC TUMOR TISSUE FROM THE SAME PATIENT

Cureline is a leading provider of primary tumor and matching recurrent or metastatic paired FFPE tumor samples. Such specimens are crucial for discovery of novel biomarkers of tumor progression and drug resistance.

Available specimen combinations:

  • Archival primary tumor FFPE block and matching recurrent /metastatic tumor FFPE block with clinical outcome data (3-10 years)

  • Prospectively procured recurrent/metastatic tumor, adjacent normal tissue (FFPE, snap frozen, RNAlater, PAXgene) and biofluids (whole blood, serum, plasma) collected in accordance with Cureline’s standard protocol or customer’s special protocol

  • Gene mutation and/or expression analysis of the tissue samples is performed upon Customer’s request.

 

TUMOR BIOSPECIMEN FROM PATIENTS TREATED WITH SPECIFIC ANTI-CANCER DRUGS WITH CLINICAL OUTCOME AND MOLECULAR PROFILING

Cureline provides tumor specimens from cancer patients receiving neoadjuvant (pre-surgery) and/or adjuvant (post-surgery) therapy. These specimens are required for elucidating the drug resistance mechanisms and development of more effective anti-cancer treatments. 

Available specimen combinations:

  • Archival primary tumor FFPE blocks from patients treated with specific chemotherapeutic agents (please see details in the Table on the back side) with clinical outcome data (3-10 years)

  • Prospectively procured treatment specific tumor, adjacent normal tissue (FFPE, snap frozen, RNAlater, PAXgene) and biofluids (whole blood, serum, plasma) collected in accordance with Cureline’s standard protocol or customer’s special protocol

We offer special molecular profiling services (Illumina, Affymetrix, Nanostring, Sequenom, NGS, etc.) upon customer’s request.